| RESEARCH ARTICLE | |
| 1. | Seropositivity of chlamydia pneumoniae in acute ischemic stroke Mehmet Gül, Arif Duran, Halil Kaya, Ali Ulvi Uca Pages 41 - 44 INTRODUCTION: The aim of our study was to investigate a relation between Acute Ischemic Stroke (AIS) and Chlamydia pneumoniae (CP). METHODS: The study was performed as a clinical prospective study. Totally, 104 healthy volunteers [76 male (73%), 28 female (27%), aged 64±14 years old] and 126 patients with AIS [64 female (51%), 76 male (73%), aged 67 ±14 years old] applied to Emergency department of Meram Medical School, Selcuk University, between January 01, 2001 and December 31, 2001 were studied. The patients and the controls were compared in respect to their CP seropositivity (CP IgG and CP IgA antibodies). RESULTS: The seropositivity of CP IgA and CP IgG was statistically significant in the patients group compared to that of the control group (p=0.006 and p=0.001 respectively). DISCUSSION AND CONCLUSION: Our results implies a relation between CP and AIS. Possibility of such a relation deeds to be more investigated. |
| 2. | Anticardiolipin antibody levels in ischemic stroke Reyhan Yılmazer, Feriha Özer, Macit Koldaş, Sibel Karşıdağ Pages 45 - 50 INTRODUCTION: Many aetiological risk factors have been known to play important roles in the development of ischemic cerebrovascular diseases. Among these risk factors, attention has been focused on high levels of anticardiolipin antibodies (ACA). This study aims to evaluate levels of ACA IgG and IgM in ischemic cerebrovascular diseases. METHODS: This study includes 60 patient and a control group of 30. In the study, for each patient brain imaging study (CT or MRI), echocardiography (TTE or TEE), doppler USG and rutin heamatological examinations were also performed. Levels of ACA IgG and IgM were studies in the serum samples taken from each patient within the first week. RESULTS: The patients (n: 60) and the control group (n: 30) were divided into age groups of under 40, 40-60 and over 60. When examined according to age, statisticaly, no significant differences were found. In the patient group average levels of IgG ACA (PLU/ml) were 4.15 for the first group, 4.40 for the second and 3.55 for the third group. Average levels of IgM ACA (PLU/ml) were 4.85, 3.10 and 1.70 respectively. As for the control group average levels ogf IgG ACA were 3.20, 3.10, 4.60 PLU/ml, and average levels of IgM ACA weere 2.60, 4.80, 1.50 PLU/ml respectively. DISCUSSION AND CONCLUSION: According to our data, there has been no significant differences statisticaly, in levels of IgG and IgM ACA between the patient and control group (p>0.05), which suggests that these levels do not constitute risk factors in stroke. |
| 3. | Results of deeply situated intracranial AVM’s treated with gamma knife Deniz Konya, Türker Kılıç, Selçuk Peker, Saruhan Çekirge, Feyyaz Baltacıoğlu, Necmettin Pamir Pages 51 - 56 INTRODUCTION: Deeply situated intracranial arteriovenous malformations have more mortality and morbidity ratios, as they present anatomical difficulties in surgical approaches. On the other hand, technically, deep location is not a complication increasing factor in radiosurgery. METHODS: In this prospective study, first 50 patients with deep AVM’s who have at least 2 year follow-up after gamma-knife treatment are evaluated. All 50 deep situated AVM’s revealed a decrease in their nidus volumes. In 44 (88%) cases AVM oclusion was complete, 4 AVM’s (8%) showed 50-80% decrease in their nidus volumes, and 2 other (4%) displayed only venous drainage. RESULTS: Six (12%) AVM cases demonstrated radiological T2 image changes around the AVM nidus, in the normal brain tissue, in 3 (6%) cases these changes caused neurologically permanent deficits. DISCUSSION AND CONCLUSION: No mortality was detected in the deeply located AVM’s and only one intracranial hemorrhage was detected in the latent period. |
| 4. | Subtypes of ischemic stroke in different age groups among young adults Canan Togay Işıkay, Deniz Tuncel, Nermin Mutluer Pages 57 - 60 INTRODUCTION: The studies concerning stroke in young adults usually included the patients under the age of 45 years. The aim of this study was to compare the risk factors and subtypes of stroke between two different age groups among young adults aged <45 years. METHODS: The files of 100 patients who were admitted with acute stroke or transient ischemic attacks (TIA) and aged 18 to 45 years were evaluated retrospectively. Patient data including stroke risk factors, clinical signs, and the results of laboratory and radiological examinations were recorded. The patients with ischemic stroke were divided into two subgroups; patients between the ages of 18-30 (Group I) and those aged over 30 years (Group II). Fisher’s exact chi-square and Student t tests were used for statistical analysis. RESULTS: There were 56 women and 44 men. Eleven patients had hemorrhagic and 89 patients had ischemic stroke or TIA. Fifteen of patients with ischemic stroke were 18-30 years of age, and 74 patients aged over 30 years. Smoking, alcoholism and ischemic stroke due to large artery atherosclerosis or small vessel occlusion were more common in men, while ischemic stroke due to uncommon causes was detected only in women (p<0.05). The proportion of ischemic stroke due to cardioembolism and uncommon causes was higher in Group I, whereas stroke due to atherosclerotic vasculopathy predominated in the 31-45 year old group (p<0.05). DISCUSSION AND CONCLUSION: Our results showed that stroke causes in young adults aged over 30 years significantly differ from those in 18-30 year old patients. The 31-45 year old patients seem to have ischemic stroke due to large artery atherosclerosis and small vessel occlusion as common as the elderly. |
| 5. | Comparison of the risk factors in the patients with extracranial and intracranial atherosclerotic cerebral infarction Talip Asil, Mahmut Kerimoğlu, İlkay Uzunca, Ufuk Utku Pages 61 - 65 INTRODUCTION: The aim of this study is investigation of the risk factors in patients with extracranial and intracranial atherosclerotic cerebral infarction. METHODS: 16 patients in whom intracranial stenosis was detected among the patients admitted to our clinic with first is cerebral infarction between 1 March 2001- 28 February 2020. It was showen that there was no source extracranial stenosis and cardioemboli in all patients. 16 patients with the same age and sex in whom extracranial atherosklerosis was detected and there was no intracranial stenosis where compared from the point of view to the risk factor. RESULTS: Range of the 16 patients with intracranial stenosis among the area who developed first cerebral infarction: 9 of them where in main territory of middle cerebral artery, 2 of them where in intracranial part of internal carotis artery, 4 of them where in basiler artery, one of them was in intracranial part of vertebral artery. No meanginful difference was found from the point of the view diabetes mellitus, hypertension, hypercholesterolemia and smoking between groups, the rate of ischemic heart disease (IHD) development was highest int the patients with extracranial atherosklerosis. DISCUSSION AND CONCLUSION: İntracranial stenosis is a condition which don’t forget in the investigation of cerebral infarction. It has been seen that developed IHD is the highest risk factor fort he extracranial atherosclerosis than fort he intracranial stenosis. |